The reference site for Famotidine

Famotidine, sold under the trade name Pepcid among others, is a histamine H2 receptor antagonist that inhibits stomach acid production.

WHAT IS Famotidine?

Famotidine is in a class of drugs called histamine receptor antagonists, and works by decreasing the amount of acid the stomach produces.

This medication is used to treat and prevent ulcers in the stomach and intestines. Furthermore, it is also administered to treat conditions in which the stomach produces too much acid and for situations in which acid comes up into the esophagus and causes heartburn, such as gastroesophageal reflux disease (GERD).

It is commonly marketed by Merck under the trade names Pepcidine® and Pepcid®.

 

Brand Name(s): Pepcid Oral; Pepcid AC
CAS nº: 76824-35-6
(fa moe’ ti deen)

 

Product Info

The sections below will provide you with more specific information and guidelines related to famotidine and its correct use. Please read them carefully.

FDA Information

Famotidine was approved by the FDA in 1995, and is available either with or without a prescription.

Note: in Oct. 2005, the FDA approved revisions to the safety labeling for famotidine chewable tablets, Gelcaps®, the original and maximum strength film-coated tablets (Pepcid AC®, made by Merck), and famotidine/calcium carbonate/magnesium hydroxide tablets (Pepcid Complete®, made by Merck) to warn of contraindications associated with their over-the-counter use.

Famotidine should not be used in patients experiencing difficult or painful swallowing, vomiting with blood, or bloody or tarry stools. These may be signs of a serious condition and should be evaluated by a physician.

Additionally, the FDA notes that famotidine should not be used concurrently with other acid reducers.

Why is this medication prescribed?

Famotidine is in a class of drugs called histamine receptor antagonists. It works by decreasing the amount of acid the stomach produces.

Famotidine is indicated for the prevention and relief of heartburn associated with acid indigestion and sour stomach. It is also indicated for the treatment of duodenal and gastric ulcers, esophagitis and heartburn due to gastroesophageal reflux disease, for pathological hypersecretory conditions, and for the maintenance of healed duodenal ulcers.

It is commonly marketed by Merck under the trade names Pepcidine® and Pepcid®.

Other uses for this medicine

This medication has not been approved for any alternative uses other than those mentioned in the product information section.

Dosage and using this medicine

Prescription famotidine comes as a tablet and a suspension (liquid) to be taken orally. It is usually taken once daily at bedtime or two to four times a day.

Over-the-counter famotidine comes as a tablet, a chewable tablet, and a capsule to be taken by mouth. It is usually taken once or twice a day, and for best results it is advised to take it 15 minutes before consuming heartburn-inducing foods or beverages.

Take famotidine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each oral dose with a full glass of water.

Chew the chewable tablets thoroughly before swallowing.

Administration with liquid is not necessary for the Pepcid RPD® orally disintegrating tablets. Just prior to taking a dose, peel open the blister pack with dry hands and place the tablet on the tongue, where it will dissolve and be swallowed with saliva.

When taking the Pepcid® suspension, shake it vigorously for 5 to 10 seconds before measuring a dose. To ensure that you get the correct dose, use a dose-measuring cup or spoon and not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not stop taking this medication without first talking to your doctor. It may take up to 8 weeks for an ulcer to heal.

What special precautions should I follow?

BEFORE TAKING FAMOTIDINE:

Tell your doctor if you have kidney disease, liver disease, trouble or pain swallowing food, vomiting with blood, or bloody or black stools.

You may not be able to take famotidine, or you may require a dosage adjustment or special monitoring during treatment, if you have any of the conditions listed above.

The Pepcid RPD® orally disintegrating tablets contain 1.05 mg of phenylalanine per 20 mg tablet and 2.10 mg of phenylalanine per 40 mg oral tablet. Patients with phenylketonuria may need to monitor their intake of this additive.

Famotidine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take famotidine without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Moreover, famotidine passes into breast milk. It is not known whether famotidine will harm a nursing infant, therefore do not take this medication without first talking to your doctor if you are breast-feeding a baby.

What should I do if I forget a dose?

If you forget a dose of prescription famotidine, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. NEVER take a double dose to make up for a missed one.

On the other hand, over-the-counter famotidine is usually taken as needed. If your doctor has told you to take over-the-counter famotidine regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Possible side effects from famotidine include:

fatigue
insomnia
muscle pain
vomiting

Tell your doctor if any of these symptoms are severe or do not go away:

dizziness
headache
diarrhea
nausea
constipation

If you experience any of the following symptoms, call your doctor immediately:

allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
easy or unusual bruising or bleeding
bleeding gums
irregular heartbeat
yellowing of the skin or eyes
a rash

Side effects other than those listed here may also occur. Please talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not allow the liquid to freeze.

Throw away any medication that is outdated or no longer needed, and throw away unused famotidine liquid after 30 days.

In case of an emergency/overdose

In the case of an overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services immediately on 911.

Symptoms of overdose may include:

nausea
vomiting
diarrhea
increased saliva production
difficulty breathing
fast heartbeat

Product Images

PICTURES OF FAMOTIDINE PILLS

Below you will find images and specific information on the principal types of famotidine that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: PEPCID AC®
Strength(s): 10 MG
Imprint: PEPCID AC
Manufacturer: J&J MERCK

Name: PEPCID AC®
Strength(s): 10 MG
Imprint: PEPCID AC
Manufacturer: J&J MERCK

Name: FAMOTIDINE
Strength(s): 20 MG
Imprint: PEPCID | 963
Manufacturer: MERCK & CO.

Name: FAMOTIDINE
Strength(s): 20 MG
Imprint: 93 | 896
Manufacturer: TEVA USA

Name: FAMOTIDINE
Strength(s): 40 MG
Imprint: 40 | 5729
Manufacturer: IVAX PHARMACEUTICALS

Name: FAMOTIDINE
Strength(s): 40 MG
Imprint: C 120
Manufacturer: PAR PHARM.

Name: FAMOTIDINE
Strength(s): 40 MG
Imprint: 93 | 897
Manufacturer: TEVA USA

Name: FAMOTIDINE
Strength(s): 40 MG
Imprint: PEPCID | MSD 964
Manufacturer: MERCK & CO.

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